3Rs and new frontiers in laboratory techniques.
نویسندگان
چکیده
Altex 31, 3/14 367 Huh, D., Matthews, B. D., Mammoto, A. et al. (2010). Reconstituting organ-level lung functions on a chip. Science 328, 1662-1668. http://dx.doi.org/10.1126/science.1188302 Huh, D., Leslie, D. C., Matthews, B. D. et al. (2012). A human disease model of drug toxicity – induced pulmonary edema in a lung-on-a-chip microdevice. Sci Trans Med 4, 159ra147. http://dx.doi.org/10.1126/scitranslmed.3004249 Kim, H. J., Huh, D., Hamilton, G. and Ingber, D. E. (2012). Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab Chip 12, 2165-2174. http://dx.doi.org/10.1039/C2LC40074J Kim, H. J. and Ingber, D. E. (2013). Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integr Biol (Camb) 5, 1130-1140. http://dx.doi. org/10.1039/c3ib40126j Kola, I. and Landis, J. (2004). Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov 3, 711-716. http://dx.doi.org/10.1038/nrd1470
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عنوان ژورنال:
- ALTEX
دوره 31 3 شماره
صفحات -
تاریخ انتشار 2014